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HIV potentiated by malaria; HIV-infected intestinal cells never recover
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HIV potentiated by malaria; HIV-infected intestinal cells never recover
HIV potentiated by malaria; HIV-infected intestinal cells never recover
12-12-2006
Two articles:
Study says malaria helps spread HIV
By LAURAN NEERGAARD, AP Medical Writer
Thu Dec 7, 2006
WASHINGTON - Malaria is fueling the spread of AIDS in Africa by boosting the HIV in people's bodies for weeks at a time, says a study that pins down the deadly interplay between the dual scourges.
It's a vicious cycle as people weakened by HIV are, in turn, more vulnerable to malaria.
University of Washington researchers who estimated the impact of the overlapping infections concluded that the interaction could be blamed for thousands of HIV infections and almost a million bouts of malaria over two decades in just one part of Kenya.
The research, published in Friday's edition of the journal Science, highlights the need for a joint attack on both epidemics.
"It's an important paper," said Dr. Anthony Fauci of the National Institutes of Health, the government's leading infectious disease specialist. "We really need to be much more serious about what we do about malaria at the same time we're serious about what we do about HIV."
Anti-malaria programs, such as a $1.2 billion U.S. initiative in its early stages, "assume a much, much greater imperative when you realize not only are you going to have an impact on one disease, but you might impact another disease," Fauci added.
Malaria sickens up to half a billion people annually and kills more than 1 million, mostly young children and mostly in Africa -- which also bears the biggest HIV burden. Sub-Saharan Africa is home to 24.7 million HIV-infected people; about 2 million died this year, according to the latest U.N. update.
Scientists long have suspected the two diseases fuel each other. The new study created a mathematical model to figure out just how much they do.
HIV is most easily spread when patients have high virus levels in their blood. A bout of malaria causes a temporary surge -- a stunning sevenfold increase -- in those levels, said lead researcher Laith Abu-Raddad, a scientist at the University of Washington.
The surge may last six weeks to eight weeks. That is longer than it takes adults in intense malaria areas, where people get the parasitic disease once or twice a year, to recover from a typical bout and feel up to sexual activity again, he said.
...
HIV-Infected Intestinal Immune Cells Never Rebound
Fri Dec 8, 2006
FRIDAY, Dec. 8 (HealthDay News) -- Within a few weeks of being infected by HIV, most of a person's memory T-cells vanish and are not likely to return even after years of antiretroviral treatment, a new study finds.
Previous research has shown that HIV infection depletes memory T-cells -- which are mostly found in the intestinal tract -- within days. In contrast, T-cells circulating in the blood typically decline over several years, according to background information in the article.
It's known that T-cells in the blood can return to normal levels when HIV patients take antiviral drugs. But it wasn't clear whether intestinal memory T-cell levels returned to normal.
In this study, researchers at the Aaron Diamond AIDS Research Center in New York City and elsewhere performed intestinal biopsies on HIV patients who had started treatment shortly after they were infected.
Reporting in the journal PLoS Medicine, the researchers found that intestinal T-cell levels remained low in 70 percent of patients even after several years of HIV treatment.
The findings indicate the doctors treating HIV patients need to watch for infections or other gastrointestinal problems that could result from prolonged impairment of intestinal immune function, the researchers said.
...
Citation: Mehandru S, Poles MA, Tenner-Racz K, Jean-Pierre P, Manuelli V, et al. (2006) Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection. PLoS Med 3(11): e484.
http://dx.doi.org/10.1371/journal.pmed.0040484
[emphases mine]
Bill Weintraub:
We already knew, per Dr Cohen, that HIV wreaks "terrible, irreversible damage" on the gut in the first few weeks of infection.
This second article tells us that Dr Cohen is right that the damage can NOT be reversed -- even by HAART.
Again, what we're seeing is HIV in the brain, HIV in the testicles, HIV in rectal secretions, HIV in the gut -- and no way of dealing with it there.
So the disease is called "manageable" -- but the question has to be asked -- Compared to what?
Clearly, prevention is preferable to treatment.
But there's NO will in the gay community to do what's necessary to actually prevent the disease.
Because the community and the community leadership are married to ANAL.
Butt-fucking.
That's what they've sold their souls and given their lives for.
Shit sex.
Now, as to the first article, you may be wondering why Americans should be concerned about malaria and its potentiating effect on HIV.
Well, while malaria has been by and large eradicated from the US, the disease is caused by a parasite, most commonly Plasmodium falciparum.
Which is a protozoan.
As it happens, there are protozoans which infect Americans, and most especially American gay men.
For example, Giardia lamblia.
According to American Family Physician,
"G. lamblia is a pear-shaped, flagellated protozoan that causes a wide variety of gastrointestinal complaints. ... Because giardiasis is spread by fecal-oral contamination, the prevalence is higher in populations with poor sanitation, close contact, and oral-anal sexual practices."
There's also Entamoeba histolytica, which causes amebiasis.
Spreading occurs via the fecal-oral route, usually by poor hygiene during food preparation or by the use of "night soil" (crop fertilization with human waste), as well as by oral-anal sexual practices. Spreading is frequent in persons who have a deficient immune system.
So: protozoan diseases are spread among gay men "by oral-anal sexual practices" aka rimming.
These diseases are common among "men into anal."
The reason why is not mysterious.
Just read any buttboy profile on an internet hook-up site:
anal and rimming are always top of the list.
And now we learn that in Africa, a protozoan disease, malaria, causes a "sevenfold increase" in the level of HIV in the blood.
Rendering the person far more infectious.
And HIV levels stay high even after the symptoms of malaria have gone away, and the person is feeling "up to sexual activity."
Anyone who's had experience of gay male promiscuity knows that gay men infected with protozoans will continue to be sexually active.
They're farting, belching, and shitting away, but they're still fucking like bunnies.
Why?
Because that's what defines their lives.
Fucking butt and eating ass.
And while the malaria study didn't look at other parasites like Giardia and E. histolytica, my suspicion is that these parasites too have a potentiating effect on HIV.
Which means that there are guys out there infected with HIV who are licking and sticking their tongues into anal sphincters; getting infected with various protozoans; and then experiencing surges in their viral load.
Making them a double threat.
These guys can give you parasites -- and they can give you AIDS.
"Spreading is frequent in persons who have a deficient immune system."
And you should be aware that you can get parasites just from oral, as we explain in Orally transmitted STD among gay men.
Hell, you can get HIV just from oral.
From a health point of view, and not to put too fine a point on it, the "sexual" practices of the buttboys are INSANE.
I wonder how many of you are still part of the insanity.
Why do I say that?
To be mean?
No.
I know what guys tell me.
Recently a guy wrote to me -- he's a nice guy -- but he still tops.
Wrestling and Frot with another strong, masculine man is his fantasy -- but he still tops.
Even though he says that when he does, he loses respect for the bottom.
No kidding.
I wrote back and said, You need to stop doing anal.
There's no point to it.
He doesn't really like it and it puts him and his partners at risk.
But he's still doing it -- basically, so far as I can tell, because it's expected.
He needs to stop.
And so do YOU.
If Wrestling and Frot are your fantasy and your dream --
start living that dream.
Not the analist nightmare.
American Family Physician: "After malaria, it is likely that E. histolytica is the world's second leading protozoan cause of death."
Bill Weintraub
© All material Copyright 2006 by Bill Weintraub. All rights reserved.
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